四甲基氯化铵

• 产品号: A13288
• CAS号: 75-57-0
• 分子式: C4H12ClN
• 分子量: 109.59778
• 纯 度: 97%, may cont. ca 3% silica as anticaking agent

产品别名

• 标题: Tetramethylammonium chloride
• IUPAC标准名: tetramethylazanium chloride
• IUPAC传统名: tetramethylammonium chloride

产品登记号

• Beilstein号: 2496575
• MDL号: MFCD00011628
• CAS号: 75-57-0
• EC号: 200-880-8

产品性质

• 纯度: 97%, may cont. ca 3% silica as anticaking agent
• 密度: 1.17
• 熔点: >300°C
• GHS危险声明: H301-H311-H315-H319-H335
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P280H-P305+P351+P338-P309-P310
• 危险公开号: 21-25-36/37/38
• RTECS编号: BS7700000
• 安全公开号: 26-36/37-45
• 保存注意事项: Hygroscopic
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2811
• 联合国危险货物包装类别(PG): II

参考文献

• Thermally-stable phase-transfer catalyst (see Appendix 2) which has been used in nucleophilic displacement reactions of aryl nitro groups with KF in tetramethylene sulfone: J. Org. Chem., 56, 6406 (1991). A detailed study of the halex Cl ^- /F ^- exchange reaction of activated aryl chlorides, for example the conversion of 1,2-dichloro-4-nitrobenzene to 2-chloro-1-fluoro-4-nitrobenzene in DMSO at 120^oC showed tetramethylammonium chloride to be superior to other common phase-transfer catalysts. It was necessary to pre-dry the catalyst to <0.2% water to avoid competition from hydrolytic displacement: Chem. Commun., 297 (1996).
• Compare also Tetraphenylphosphonium bromide, A15860 and Tetraphenylphosphonium chloride, A10575.