三正丁基氯化锡

• 产品号: A10746
• CAS号: 1461-22-9
• 分子式: C12H27ClSn
• 分子量: 325.49678
• 纯 度: 96%

产品别名

• 标题: Tri-n-butyltin chloride
• IUPAC标准名: tributylstannylium chloride
• IUPAC传统名: tributylstannylium chloride
• 别名: Chlorotri-n-butylstannane; Chlorotri-n-butyltin

产品登记号

• EC号: 215-958-7
• MDL号: MFCD00000521
• Beilstein号: 3535715
• CAS号: 1461-22-9

产品性质

• 纯度: 96%
• 沸点: 171-173°C/25mm
• 密度: 1.200
• 闪点: 120°C(248°F)
• 熔点: -19°C
• 折射率: 1.4910
• GHS危险声明: H301-H312-H315-H319-H372-H400-H410
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P260-P301+P310-P305+P351+P338-P302+P352-P405-P501A
• 危险公开号: 21-25-36/38-48/23/25-50/53
• RTECS编号: WH6820000
• 安全公开号: 36/37/39-45-60-61
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2788
• 联合国危险货物包装类别(PG): II

参考文献

• Reaction with Grignard or lithium reagents gives alkyl or aryl stannanes.
• Organostannanes undergo the Stille coupling reaction, in the presence of Pd catalysts, such as trans-Dichlorobis(triphenylphosphine)palladium(II), 10491, or Tetrakis(triphenylphosphine)palladium(0), 10548, with aryl halides: Angew. Chem. Int. Ed., 25, 508 (1986); J. Org. Chem., 52, 422 (1987), aryl triflates: J. Am. Chem. Soc., 106, 4630 (1984); 108, 3033 (1986); 109, 5478 (1987); Org. Synth. Coll., 9, 553 (1998), or aryl fluorosulfonates: J. Org. Chem., 56, 3493 (1991). LiCl is added in the reaction with triflates to prevent decomposition of the catalyst. These reactions are of wide scope (coupling also occurs with vinyl, allyl or benzyl halides), take place under very mild conditions, and a variety of other functional groups can be tolerated. For recent reviews of the Stille reaction, see: Adv. Met.-Org. Chem., 5, 1 (1996); Org. React., 50, 1 (1997).
• For use in stannylation of allylic chlorides via the ultrasound-promoted Barbier reaction with Mg, see: Chem. Lett., 1857 (1986); Org. Synth. Coll, 9, 707 (1998). For an example of stannylation of indoles as a route to 2-substituted indoles, see 1-Methylindole, A12605.
• See also: A. G. Davies, Organotin Chemistry, Wiley-VCH, N. Y. (1997); H. Nozaki in Organometallics in Synthesis, M. Schlosser, Ed., Wiley, N.Y. (1994), p535; (reviews): Tetrahedron, 45, 909 (1989); J. Organomet. Chem., 437, 23 (1992).