Tauroursodeoxycholic-2,2,3,4,4-d5 Acid

• 产品号: T009202
• 分子式: C26H45NO6S
• 分子量: 499.7036
• 保 存: -20°C Freezer, Under Inert Atmosphere

产品别名

• 标题: Tauroursodeoxycholic-2,2,3,4,4-d5 Acid
• IUPAC标准名: 2-[(4R)-4-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
• IUPAC传统名: 2-[(4R)-4-[(1S,2S,5R,7R,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyl(4,4,5,6,6-^2H₅)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-14-yl]pentanamido]ethanesulfonic acid
• 别名: 3α,7β-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide-d5; 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic-d5 Acid; Ursodeoxycholyltaurine-d5

产品性质

• 外观: White to Off-White Solid
• 熔点: 154-158°C
• 溶解度: DMSO
• 溶解度: Methanol
• 溶解度: Water
• 保存条件: -20°C Freezer, Under Inert Atmosphere

产品详细信息

详细说明 (English)

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.

参考文献

• Alvarez, E., et al.: J. Biol. Chem., 266, 15277 (1991)
• Alvaro, D., et al.: J. Clin. Invest., 96, 665(1991)
• Alpini, G., et al.: Hepatology, 34, 868 (1991)
• Higuchi, H., et al.: J. Biol. Chem., 278, 454 (2003)