N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester

• 产品号: S689840
• CAS号: 21994-89-8
• 分子式: C12H13N3O8
• 分子量: 327.24692

产品别名

• 标题: N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester
• IUPAC标准名: 2,5-dioxopyrrolidin-1-yl 3-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}amino)propanoate
• IUPAC传统名: 2,5-dioxopyrrolidin-1-yl 3-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}amino)propanoate
• 别名: N-[[N-[(Succinimidooxy)carbonyl]-β-alanyl]oxy]succinimide; 1-[3-[[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]amino]-1-oxopropoxy]-2,5-pyrrolidinedione; N-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-β-alanine 2,5-Dioxo-1-pyrrolidinyl Ester

产品登记号

• CAS号: 21994-89-8

产品详细信息

详细说明 (English)

A short, amino reactive homobifunctional crosslinking reagent. Crosslinking distance 8.3 Å. It is useful in polymer coupling to proteins, because it may lead to a better selectivity among all the amino groups present in a protein, thus yielding less heterogeneous PEG-protein conjugates mixture because only the most nucleophilic and solvent exposed amines can react.

参考文献

• Gross, H., et al.: Tetrahedron, 24, 6935 (1968)
• Clark, R., et al.: J. Biol. Chem., 271, 21969 (1968)
• Guiotto, A., et al.: Bioorg. Med. Chem., 12, 5031 (1968)