PD-166866

• 产品号: P217550
• CAS号: 192705-79-6
• 分子式: C20H24N6O3
• 分子量: 396.44296
• 保 存: Refrigerator

产品别名

• 标题: PD-166866
• IUPAC标准名: 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
• IUPAC传统名: 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
• 别名: N-[2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea

产品登记号

• CAS号: 192705-79-6

产品性质

• 外观: Off-White Solid
• 熔点: 291-293°C (dec.)
• 溶解度: DMSO
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF).

参考文献

• Zhu, X., et al.: Science, 251, 90 (1991)
• Davies, D.E., et al.: Biochem. Pharmacol., 51, 1101 (1991)
• Panek, R.L., et al.: J. Pharmacol. Exp. Ther., 286, 569 (1991)
• Iacoangeli, A., et al.: Biochimie, 82, 35 (1991)