PD-123319 Bis(trifluoroacetate) Salt Hydrate

• 产品号: P217475
• 分子式: C33H33F3N4O5
• 分子量: 622.6341296
• 保 存: Refrigerator

产品别名

• 标题: PD-123319 Bis(trifluoroacetate) Salt Hydrate
• IUPAC标准名: (6S)-1-{[4-(dimethylamino)-3-methylphenyl]methyl}-5-(2,2-diphenylacetyl)-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid; trifluoroacetic acid
• IUPAC传统名: (6S)-1-{[4-(dimethylamino)-3-methylphenyl]methyl}-5-(2,2-diphenylacetyl)-4H,6H,7H-imidazo[4,5-c]pyridine-6-carboxylic acid; trifluoroacetic acid
• 别名: (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319 Bis(trifluoroacetate) Salt Hydrate

产品性质

• 外观: Pale Beige Solid
• 熔点: 111-114°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: Refrigerator

产品详细信息

详细说明 (English)

A selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has

参考文献

• Carmeiros-Ramos, M.S. et al.: Bas. Res, Cardiol., 105, 325 (2010)
• Kagawa, T. et al.: Nephrol., 13, 309 (2010)
• Cohen, E.P. et al.: Transl. Res., 150, 106 (2010)