ent-Lamivudine

• 产品号: L172505
• CAS号: 134680-32-3
• 分子式: C8H11N3O3S
• 分子量: 229.25624
• 保 存: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品别名

• 标题: ent-Lamivudine
• IUPAC标准名: 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one
• IUPAC传统名: 2'3' dideoxy 3' thiacytidine
• 别名: 4-Amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; cis(+)-2-Hydroxymethyl-5-(cytosin-1-yl)-1,3-oxathiolane; (2S-cis)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; 2',3'-Dideoxy-3'-thiacytidine; (+)-BCH 189; 2'-Deoxy-3'-thiacytidine; 3TC; NSC 620753

产品登记号

• CAS号: 134680-32-3

产品性质

• 外观: Off-White to Pale Yellow Solid
• 熔点: 164-166°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Hygroscopic, Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

An enantiomer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.

参考文献

• Pepe, G. et al.: Eur. J. Med. Chem., 31, 775 (1996)
• Marr, E. et al.: Antiviral Res., 28, 1 (1996)
• Parikh, U.M. et al.: Antimicrob. Agents Chemother., 49, 1139 (1996)