3α-Hydroxy Tibolone

• 产品号: H964250
• CAS号: 100239-44-9
• 分子式: C21H30O2
• 分子量: 314.4617
• 保 存: Controlled Substance, -20°C Freezer

产品别名

• 标题: 3α-Hydroxy Tibolone
• IUPAC标准名: (1S,5R,9R,10R,11S,14R,15S)-14-ethynyl-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-2(7)-ene-5,14-diol
• IUPAC传统名: (1S,5R,9R,10R,11S,14R,15S)-14-ethynyl-9,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-2(7)-ene-5,14-diol
• 别名: (3α,7α,17α)-7-Methyl-19-norpregn-5(10)-en-20-yne-3,17-diol; Org 4094; (3α,7α,17α)-3,17-Dihydroxy-7-methyl-19-norpregn-5(10)-en-20-yl-3-one

产品登记号

• CAS号: 100239-44-9

产品性质

• 外观: Off-White Solid
• 熔点: 72-74°C
• 溶解度: Dichloromethane
• 溶解度: Ethyl Acetate
• 溶解度: Methanol
• 保存条件: Controlled Substance, -20°C Freezer

产品详细信息

详细说明 (English)

A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.

参考文献

• Belman, S., et al.: Cancer Res., 32, 450 (1972)
• Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1972)
• Hoyte, R., et al.: Steroids, 58, 13 (1972)
• Sandker, G., et al.: Xenobiotica, 24, 143 (1972)
• Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (20