Homoharringtonine-13C,d3

• 产品号: H596502
• 分子式: C29H39NO9
• 分子量: 546.61391484

产品别名

• 标题: Homoharringtonine-13C,d3
• IUPAC标准名: (2S,3S,6R)-4-(^1^3C,^2H₃)methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^2,^6.0^6,^1^0.0^1^5,^1^9]icosa-1(20),4,13,15(19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate
• IUPAC传统名: (2S,3S,6R)-4-(^1^3C,^2H₃)methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^2,^6.0^6,^1^0.0^1^5,^1^9]icosa-1(20),4,13,15(19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate
• 别名: Omacetaxine Mepesuccinate-13C,d3; Ceflatonin-13C,d3; Cephalotaxine-13C,d3 4-Methyl (2R)-2-Hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (Ester); NSC 141633-13C,d3; CGX 635-13C,d3

产品详细信息

详细说明 (English)

Homoharringtonine (HHT) combined with some botanical drugs could induce cancer cells to resemble normal cells. HHT was prepared by a semi-synthetic method from Cephalotaxine, a major alkaloid of Cepahlotaxus species through the formation of α-ketoester ha

参考文献

• Baaske, D., et al.: Antimicrob. Agents Chemother., 12, 298 (1977)
• Tipping, A., et al.: Leukemia, 16, 2349 (1977)
• Marin, D., et al.: Cancer, 103, 1850 (1977)
• Levy, V., et al.: Br. J. Cancer, 95, 253 (1977)
• de Lavallade, H., et al.: Blood, 2779 (1977)