红霉素

• 产品号: 45673
• CAS号: 114-07-8
• 分子式: C37H67NO13
• 分子量: 733.92678
• 纯 度: ≥95.0% (NT)

产品别名

• 标题: Erythromycin
• IUPAC标准名: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• IUPAC传统名: erythromycin

产品登记号

• CAS号: 114-07-8
• MDL号: MFCD00084654
• PubChem SID: 24869225
• Beilstein号: 75279
• EC号: 204-040-1

产品性质

• Empirical Formula (Hill Notation): C37H67NO13
• 纯度: ≥95.0% (NT)
• 相关基因信息: human ... ABCB1(5243), CYP3A4(1576), MLNR(2862)mouse ... Abcb1a(18671), Abcb1b(18669)
• 熔点: 133-135 °C
• 比旋光度: [α]20/D -75±4°, c = 2% in ethanol
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS编号: KF437500
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
Inhibits bacterial protein synthesis by binding to the ribosomes1; Inducible erythromycin resistance in bacteria2

详细说明 (简体中文)

Biochem/physiol Actions
Mode of Action: Inhibits elongation at transpeptidation step.Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Other Notes
Macrolide antibiotic.
通过结合到核糖体上抑制细菌蛋白合成1；在细菌中可诱导红霉素抗性2