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bisBenzimide H 33342 trihydrochloride

产品号 14533 公司名称 Sigma Aldrich
CAS号 23491-52-3 公司网站 http://www.sigmaaldrich.com
分子式 C29H35Cl3N6O 电 话 1-800-521-8956
分子量 589.9868 传 真
纯 度 ≥97.0% (HPLC) 电子邮件
保 存 Chembase数据库ID: 130884

产品价格信息

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产品别名

标题
bisBenzimide H 33342 trihydrochloride
IUPAC标准名
2-(4-ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1,4-dihydroquinazolin-2-yl]-1,4-dihydroquinazoline trihydrochloride
IUPAC传统名
2-(4-ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1,4-dihydroquinazolin-2-yl]-1,4-dihydroquinazoline trihydrochloride
别名
bisBenzimide
Hoechst 33342
2′-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi-1H-benzimidazole trihydrochloride
HOE 33342

产品登记号

EC号 245-691-1
MDL号 MFCD00012678
PubChem SID 24848717
Beilstein号 1234011
CAS号 23491-52-3

产品性质

Empirical Formula (Hill Notation) C27H28N6O · 3HCl · xH2O
级别 for fluorescence
纯度 ≥97.0% (HPLC)
荧光 λex 340 nm; λem 510 nm
荧光 λex 355 nm; λem 465 nm in TE buffer; DNA
GHS危险品标识 GHS05
GHS危险品标识 GHS07
GHS警示词 Danger
GHS危险声明 H302-H315-H318-H335
欧盟危险性物质标志 有害性(Harmful) 有害性(Harmful) (Xn)
MSDS下载 下载链接
个人保护装置 dust mask type N95 (US), Eyeshields, Gloves
GHS警示性声明 P261-P280-P305 + P351 + P338
危险公开号 22-37/38
RTECS编号 DT4200000
安全公开号 22-36/37
保存温度 2-8°C
德国WGK号 3

产品详细信息

详细说明 (English)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry.Excitation max. = 346 nmEmission max. = 460 nm
bisBenzimide H 33342 trihydrochloride can be used to study biochemicals and reagents, fluorescent probes, labels, particles and stains, luminescent compounds and detection and wavelength index. bisBenzimide H 33342 trihydrochloride, Hoechst 33342, has been used in a study to investigate the effects of inorganic and organic arsenic compounds on human T-lymphoblastoid leukemia cells. Hoechst 33342 has also been used in a study to examine the effects of 9 calcium antagonists on ABCG2/BCRP-mediated resistance and transport in HeLa and SN-38-resistant HeLa (HeLa/SN100) cells, overexpressing ABCG2/BCRP.
Biochem/physiol Actions
Membrane-permeable, fluorescent DNA stains with low cytotoxicity that intercalate in A-T regions of DNA.
Other Notes
Suitable for vital DNA staining of a variety of cell types1,2; As a probe of membrane permeability in mammalian cells3
详细说明 (简体中文)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry.Excitation max. = 346 nmEmission max. = 460 nm
bisBenzimide H 33342 trihydrochloride can be used to study biochemicals and reagents, fluorescent probes, labels, particles and stains, luminescent compounds and detection and wavelength index. bisBenzimide H 33342 trihydrochloride, Hoechst 33342, has been used in a study to investigate the effects of inorganic and organic arsenic compounds on human T-lymphoblastoid leukemia cells. Hoechst 33342 has also been used in a study to examine the effects of 9 calcium antagonists on ABCG2/BCRP-mediated resistance and transport in HeLa and SN-38-resistant HeLa (HeLa/SN100) cells, overexpressing ABCG2/BCRP.
Biochem/physiol Actions
Membrane-permeable, fluorescent DNA stains with low cytotoxicity that intercalate in A-T regions of DNA.
Other Notes
Suitable for vital DNA staining of a variety of cell types1,2; As a probe of membrane permeability in mammalian cells3

参考文献