Biochem/physiol Actions Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes. The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1. Other Notes Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats2 Sales restrictions may apply Substrates Choline acetyltransferase substrate |
Biochem/physiol Actions Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes. The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1. Other Notes Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats2 Sales restrictions may apply Substrates 胆碱乙酰基转移酶底物 |