N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide_分子结构_CAS_)

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N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide
产品号	A9968	公司名称	Sigma Aldrich
CAS号		公司网站	http://www.sigmaaldrich.com
分子式	C27H38N6O12	电话	1-800-521-8956
分子量	638.62362	传真
纯度	≥95%	电子邮件
保存		Chembase数据库ID: 106632

产品价格信息

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产品别名

标题

N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide

IUPAC标准名

(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-nitrophenyl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid

IUPAC传统名

(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-nitrophenyl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid

别名

Ac-IETD-pNA

产品登记号

MDL号	MFCD01318840

产品性质

Empirical Formula (Hill Notation)	C27H38N6O12
纯度	≥95%
相关基因信息	human ... CARD8(22900), CASP8(841), CASP8AP2(9994), CFLAR(8837), GZMB(3002)mouse ... CFLAR(117279), GZMB(171528)rat ... CASP8(12370), CFLAR(12633), GZMB(14939), RGD1561819(502004), RGD1562700(502007)
MSDS下载	下载链接
个人保护装置	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
保存温度	-20°C
德国WGK号	3

产品详细信息

详细说明 (English)

Amino Acid Sequence
NAc-Ile-Glu-Thr-Asp-pNA
Application
Chromogenic substrate for caspase 8 and granzyme B.
Biochem/physiol Actions
IETD is the sequence of amino acid residues 172-175 of procaspase 3, which is cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.

详细说明 (简体中文)