Thiazolyl Blue Tetrazolium Bromide

• 产品号: M2128
• CAS号: 298-93-1
• 分子式: C18H16BrN5S
• 分子量: 414.32214
• 纯 度: 98%

产品别名

• 标题: Thiazolyl Blue Tetrazolium Bromide
• IUPAC标准名: 2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-3H-1,2λ^5,3,4-tetrazol-2-ylium bromide
• IUPAC传统名: 2-(dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-1,2λ^5,3,4-tetrazol-2-ylium bromide
• 别名: MTT; 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide

产品登记号

• EC号: 206-069-5
• PubChem SID: 24896603
• CAS号: 298-93-1
• MDL号: MFCD00011964
• Beilstein号: 4081397

产品性质

• Empirical Formula (Hill Notation): C18H16BrN5S
• 纯度: 98%
• 熔点: 195 °C (dec.)(lit.)
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335-H341
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• GHS警示性声明: P261-P281-P305 + P351 + P338
• 危险公开号: 36/37/38-68
• RTECS编号: XF8060000
• 安全公开号: 26-36/37
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Packaging
1, 5, 10 g in glass bottle
100, 250, 500 mg in glass bottle
Application
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9

详细说明 (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
包装
1, 5, 10 g in glass bottle
100, 250, 500 mg in glass bottle
Application
Thiazolyl Blue Tetrazolium Blue (MTT) may be used in measurement of cell proliferation.1,2,3,4,5 MTT produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells. The blue crystals are solubilized with acidified isopropanol and the intensity is measured colorimetrically at 570 nm. MTT has been used as a histochemical/cytochemical reagent6 and for the detection of NAD.7 ADP-linked enzyme systems in tissue cannot be detected with MTT, due to binding of the cation by the cyanide trap used.8 MTT is rapidly reduced to the formazan, which chelates with nickel, copper, and cobalt; the cobalt chelate has been used in oxidative systems.9