NGB 2904 hydrochloride

• 产品号: SML0066
• CAS号: 189061-11-8
• 分子式: C28H30Cl3N3O
• 分子量: 530.9163
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: NGB 2904 hydrochloride
• IUPAC标准名: N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-9H-fluorene-2-carboxamide hydrochloride
• IUPAC传统名: N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}-9H-fluorene-2-carboxamide hydrochloride
• 别名: N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide hydrochloride

产品登记号

• MDL号: MFCD09971107
• CAS号: 189061-11-8

产品性质

• Empirical Formula (Hill Notation): C28H29Cl2N3O·HCl
• 纯度: ≥98% (HPLC)
• 外观: white to tan powder
• 溶解度: DMSO: ≥25 mg/mL
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Biochem/physiol Actions
NGB 2904 is a potent and selective dopamine D3 receptor antagonist with a D3/D2 ratio of 800 for rat and high binding affinity (1.4 nM) at the hD3 receptor with 150-fold selectivity for primate D3 receptors over primate D2L receptors. It attenuates the rewarding effects of cocaine and methamphetamine.

详细说明 (简体中文)

Biochem/physiol Actions
NGB 2904 is a potent and selective dopamine D3 receptor antagonist with a D3/D2 ratio of 800 for rat and high binding affinity (1.4 nM) at the hD3 receptor with 150-fold selectivity for primate D3 receptors over primate D2L receptors. It attenuates the rewarding effects of cocaine and methamphetamine.