Auraptene

• 产品号: A9861
• CAS号: 495-02-3
• 分子式: C19H22O3
• 分子量: 298.37618
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: Auraptene
• IUPAC标准名: 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]-2H-chromen-2-one
• IUPAC传统名: 7-[(3,7-dimethylocta-2,6-dien-1-yl)oxy]chromen-2-one
• 别名: 7-Geranyloxycoumarin; 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one; Aurapten

产品登记号

• CAS号: 495-02-3
• MDL号: MFCD00075948

产品性质

• Empirical Formula (Hill Notation): C19H22O3
• 纯度: ≥98% (HPLC)
• 外观: white to off-white powder
• 溶解度: DMSO: >20 mg/mL
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).

详细说明 (English)

Biochem/physiol Actions
Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).