NP603

• 产品号: N2290
• CAS号: 949164-80-1
• 分子式: C26H26N2O5
• 分子量: 446.49504
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: NP603
• IUPAC标准名: 3-(5-{[6-(3,5-dimethoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
• IUPAC传统名: 3-(5-{[6-(3,5-dimethoxyphenyl)-2-oxo-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
• 别名: 5-[[6-(3,5-Dimethoxyphenyl)-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; (Z)-3-(5-(6-(3,5-Dimethoxyphenyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrol-3-yl)-propionic acid

产品登记号

• CAS号: 949164-80-1
• MDL号: MFCD18632551

产品性质

• Empirical Formula (Hill Notation): C26H26N2O5
• 纯度: ≥98% (HPLC)
• 外观: orange-red powder
• 溶解度: DMSO: ≥30 mg/mL
• GHS危险声明: H413
• 保存温度: 2-8°C
• 德国WGK号: 3

产品详细信息

详细说明 (简体中文)

Biochem/physiol Actions
NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. NP603 is a very weak inhibitor of EGFR (IC50 >100 μM).

详细说明 (English)

Biochem/physiol Actions
NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. NP603 is a very weak inhibitor of EGFR (IC50 >100 μM).