PD-166866

• 产品号: PZ0114
• CAS号: 192705-79-6
• 分子式: C20H24N6O3
• 分子量: 396.44296
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: PD-166866
• IUPAC标准名: 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
• IUPAC传统名: 1-[2-amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
• 别名: 1-[2-Amino-6-(3,5-dimethoxyphenyl)-pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butyl urea

产品登记号

• CAS号: 192705-79-6
• MDL号: MFCD12922514

产品性质

• Empirical Formula (Hill Notation): C20H24N6O3
• 纯度: ≥98% (HPLC)
• 外观: off-white to light tan
• 溶解度: DMSO: ≥10 mg/mL
• GHS警示词: Warning
• GHS危险声明: H302
• 欧盟危险性物质标志: 有害性(Harmful) (Xn)
• 危险公开号: 22
• 保存温度: 2-8°C
• 德国WGK号: 1

产品详细信息

详细说明 (English)

Biochem/physiol Actions
PD-166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.
Legal Information
Sold for research purposes under agreement from Pfizer Inc.

详细说明 (简体中文)

Biochem/physiol Actions
PD-166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4.
Legal Information
Sold for research purposes under agreement from Pfizer Inc.