AICAR

• 产品号: A9978
• CAS号: 2627-69-2
• 分子式: C9H14N4O5
• 分子量: 258.23126
• 纯 度: ≥98% (HPLC)

产品别名

• 标题: AICAR
• IUPAC标准名: 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4-carboxamide
• IUPAC传统名: acadesine
• 别名: 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide; Acadesine

产品登记号

• EC号: 220-097-5
• CAS号: 2627-69-2
• MDL号: MFCD00869751
• PubChem SID: 24724407

产品性质

• Empirical Formula (Hill Notation): C9H14N4O5
• 纯度: ≥98% (HPLC)
• 运输包装: dry ice
• 外观: tan powder
• 熔点: 214-215 °C
• 溶解度: H2O: >7 mg/mL
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 保存温度: -20°C
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

详细说明 (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.