Efonidipine hydrochloride monoethanolate

• 产品号: E0159
• 分子式: C36H45ClN3O8P
• 分子量: 714.184561
• 纯 度: ≥98% (HPLC)
• 保 存: desiccated

产品别名

• 标题: Efonidipine hydrochloride monoethanolate
• IUPAC标准名: ethanol 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2λ^5-dioxaphosphinan-2-yl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate hydrochloride
• IUPAC传统名: efonidipine ethyl alcohol hydrochloride

产品登记号

• MDL号: MFCD00875717

产品性质

• Empirical Formula (Hill Notation): C34H38N3O7P · HCl · C2H5OH
• 纯度: ≥98% (HPLC)
• 外观: pale yellow powder
• 溶解度: DMSO: >5 mg/mL
• 溶解度: H2O: insoluble
• 个人保护装置: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• 保存条件: desiccated
• 保存温度: 2-8°C
• 德国WGK号: 1

产品详细信息

详细说明 (English)

Biochem/physiol Actions
Racemic efonidipine has both L-type and T-type calcium channel blocking activity. The R(-)-isomer appears to be very selective for T-type calcium channel. The S(+)-isomer inhibits the expressed Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1 channel currents almost equally.1

详细说明 (简体中文)

Biochem/physiol Actions
Racemic efonidipine has both L-type and T-type calcium channel blocking activity. The R(-)-isomer appears to be very selective for T-type calcium channel. The S(+)-isomer inhibits the expressed Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1 channel currents almost equally.1