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Brefeldin A_分子结构_CAS_20350-15-6)
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Brefeldin A

产品号 B5936 公司名称 Sigma Aldrich
CAS号 20350-15-6 公司网站 http://www.sigmaaldrich.com
分子式 C16H24O4 电 话 1-800-521-8956
分子量 280.35936 传 真
纯 度 电子邮件
保 存 Chembase数据库ID: 126224

产品价格信息

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产品别名

标题
Brefeldin A
IUPAC标准名
(1R,6S,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
IUPAC传统名
brefeldin A
别名
γ,4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid λ-lactone
Ascotoxin
Cyanein
Decumbin
BFA

产品登记号

MDL号 MFCD12913297
Beilstein号 25191
CAS号 20350-15-6

产品性质

生物来源 from Penicillium brefeldianum
浓度 10 mg/mL in DMSO
Empirical Formula (Hill Notation) C16H24O4
运输包装 wet ice
无菌消毒 0.2 μm filtered
闪点 87 °C
闪点 188.6 °F
MSDS下载 下载链接
个人保护装置 Eyeshields, Faceshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
保存温度 2-8°C
德国WGK号 2

产品详细信息

详细说明 (English)
Application
Brefeldin A is produced from Penicillium brefeldianum and is used to study protein transport.
Biochem/physiol Actions
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum. 1 BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
详细说明 (简体中文)
Application
Brefeldin A is produced from Penicillium brefeldianum and is used to study protein transport.
Biochem/physiol Actions
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum. 1 BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.
Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus. BFA is an activator of the sphingomyelin cycle. Brefeldin A-mediated apoptosis has been observed in human tumor cells.

参考文献