N-(4-Anilino-1-naphthyl)maleimide

• 产品号: 10420
• CAS号: 50539-45-2
• 分子式: C20H14N2O2
• 分子量: 314.33736
• 纯 度: ≥99.0% (HPLC)

产品别名

• 标题: N-(4-Anilino-1-naphthyl)maleimide
• IUPAC标准名: 1-[4-(phenylamino)naphthalen-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione
• IUPAC传统名: 1-[4-(phenylamino)naphthalen-1-yl]pyrrole-2,5-dione
• 别名: 1-[4-(phenylamino)naphthyl]-1H-pyrrole-2,5-dione; 1-(4-Anilino-1-naphtyl)-3-pyrroline-2,5-dione; N-(1-Anilinonaphthyl-4)-maleimide; ANM; 1-[4-(phenylamino)naphthalen-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione; N-(1-Anilinophenyl)maleimide; N-[4-(Phenylamino)-1-naphtyl]maleimide

产品登记号

• EC号: 256-618-8
• MDL号: MFCD00042694
• PubChem SID: 24846431
• CAS号: 50539-45-2
• Beilstein号: 1487865

产品性质

• Empirical Formula (Hill Notation): C20H14N2O2
• 产品线: BioReagent
• 纯度: ≥99.0% (HPLC)
• 适用性: suitable for fluorescence
• GHS警示词: Warning
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 个人保护装置: dust mask type N95 (US), Eyeshields, Gloves
• GHS警示性声明: P261-P305 + P351 + P338
• 危险公开号: 36/37/38
• 安全公开号: 26-36
• 德国WGK号: 3

产品详细信息

详细说明 (English)

Other Notes
Fluorescent hydrophobic probe for thiol groups in proteins; Review7,8
Application
ANM has been used to label muscle fibers to determine the conformational changes between the rigor state and the relaxed state 1>. This probe provides an excellent signal for monitoring changes in environment during protein refolding 2 because it′s fluorescence quantum yield is highly sensitive to solvent polarity 3. A non fluorescent compound which becomes strongly fluorescent upon selective reaction wih thiols 3. ANM can be used to monitor heterodimerization of the α and β subunits of luciferase. 2. Applied to monitor protein interactions using FRET 4 and protein conformational changes using nanosecond time-resolved fluorescence experiments 5. This probe has been used to determine the reactivity of the sulphydrl groups in tryptophanse 6.

详细说明 (简体中文)

Other Notes
Fluorescent hydrophobic probe for thiol groups in proteins; Review7,8
Application
ANM has been used to label muscle fibers to determine the conformational changes between the rigor state and the relaxed state 1>. This probe provides an excellent signal for monitoring changes in environment during protein refolding 2 because it′s fluorescence quantum yield is highly sensitive to solvent polarity 3. A non fluorescent compound which becomes strongly fluorescent upon selective reaction wih thiols 3. ANM can be used to monitor heterodimerization of the α and β subunits of luciferase. 2. Applied to monitor protein interactions using FRET 4 and protein conformational changes using nanosecond time-resolved fluorescence experiments 5. This probe has been used to determine the reactivity of the sulphydrl groups in tryptophanse 6.