Ciclosporin

• 产品号: Ciclosporin
• CAS号: 59865-13-3
• 分子式: C62H111N11O12
• 分子量: 1202.61124

产品别名

• 标题: Ciclosporin
• IUPAC标准名: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
• IUPAC传统名: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
• 商标名: Neoral, Sandimmune

产品登记号

• KEGG ID: D00184
• ATC码: S01XA18
• CAS号: 59865-13-3
• CHEMBL: 160
• 美国药典/FDA物质标识码: 83HN0GTJ6D
• PubChem CID: 5284373
• Chemspider ID: 4447449
• DrugBank ID: DB00091
• 维基百科标题: Ciclosporin
• Medline Plus: a601207
• ATC码: L04AD01

产品性质

• 给药途径: Oral, IV, ophthalmic
• 生物利用度: Variable
• 排泄: Biliary
• 半衰期: Variable (about 24 hours)
• 法定药品分级: S4 (Australia)
• 法定药品分级: POM (UK)
• 法定药品分级: Rx-only (US)
• 代谢: Hepatic
• 妊娠期药物分类: C (US)
• 妊娠期药物分类: C (Australia)