oxolane borane

• ChemBase编号: 136015
• 分子式: C4H11BO
• 平均质量: 85.94054
• 单一同位素质量: 86.09029537
• SMILES: B.C1CCOC1
• Canonical SMILES: C1CCCO1.B
• InChI: InChI=1S/C4H8O.BH3/c1-2-4-5-3-1;/h1-4H2;1H3
• InChIKey: RMCYTHFAWCWRFA-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: oxolane borane
• IUPAC传统名: tetrahydrofuran borane
• 别名: 硼烷四氢呋喃络合物 溶液; 四氢呋喃硼烷络合物,1M THF溶液, 氩气下可重封的ChemSeal™瓶包装; 四氢呋喃硼烷,1M 在四氢呋喃溶剂中,以5mmol NaBH; Borane tetrahydrofuran complex solution; Borane-tetrahydrofuran complex, 1M soln. in THF; Trihydro(tetrahydrofuran)boron; BTHF; Borane-tetrahydrofuran complex, 1M soln. in THF, stab. with 5mmol NaBH4

登记号

• CAS号: 14044-65-6
• EC号: 237-881-8
• MDL号: MFCD00012429
• Beilstein号: 3668402
• PubChem SID: 24883750; 24850560; 162230286
• PubChem CID: 11062302

理论计算性质

• 质子受体: 1
• 质子供体: 0
• LogD (pH = 5.5): 0.53034693
• LogD (pH = 7.4): 0.53034693
• Log P: 0.53034693
• 摩尔折射率: 20.5535 cm^3
• 极化性: 8.060449 Å^3
• 极化表面积: 9.23 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 外观: Liquid
• 沸点: 35 °C
• 闪点: 1 °F; 1.4 °F; -17 °C; -21°C(-8°F); -22 °F; -30 °C
• 密度: 0.846 g/mL at 25 °C; 0.87 g/mL at 20 °C; 0.878; 0.880 g/mL at 25 °C; 0.898 g/mL at 25 °C

安全信息

• 保存注意事项: Air & Moisture Sensitive
• 欧盟危险性物质标志: 易燃性(Flammable) (F); 刺激性(Irritant) (Xi); 有害性(Harmful) (Xn)
• 联合国危险货物编号: 3399; UN3148
• 德国WGK号: 3
• 联合国危险货物等级: 4.3
• 联合国危险货物包装类别(PG): 1; I
• 危险公开号: 11-14/15-19-22-36/37/38-66-67; 11-14/15-19-22-37/38-41; 11-14/15-19-36/37; 11-14/15-19-37/38-41; 14/15-19-22-36/37/38
• 安全公开号: 16-26-29-33-36; 16-26-33-43; 16-26-43; 16-33-36/37/39-7/9; 7/8-9-16-23-26-30-33-36/37/39-43-60
• TSCA收录: 是
• GHS危险品标识: GHS02; GHS05; GHS07; GHS08
• GHS警示词: Danger
• GHS危险声明: H225-H260-H302-H315-H318-H335; H225-H260-H318-H315-H351-H335-H303; H225-H260-H319-H335
• GHS警示性声明: P210-P223-P231 + P232-P261-P370 + P378-P422; P210-P231+P232-P303+P361+P353-P305+P351+P338-P405-P501A
• 个人保护装置: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• RID/ADR: UN 3399 4.3/PG 1
• 欧盟补充危害声明: May form explosive peroxides.
• 保存温度: 2-8°C

产品相关信息

• 纯度: 95+%
• 浓度: ~1 M in THF; 1.0 M in THF; 1.5 M in THF and ether; 1M soln. in THF
• 级别: purum; technical grade
• 包装: packaged under Argon in resealable ChemSeal? bottles
• 杂质: ≤20% diethylether
• 其他组分: <0.005 M sodium borohydride as stabilizer; 0.005 M N-Isopropyl-N-methyl-tert-butylamine as stabilizer
• 线性分子式: BH3OC4H8

详细说明

Sigma Aldrich - 176192

Application
用于将聚酰胺纤维表面的酰胺基还原为仲胺。1
New, Safer, NIMBA-Stabilized BH3 THF Solutions
包装
4×25, 100, 800 mL in Sure/Seal™

Sigma Aldrich - 650412

Application
作为一种新型稳定剂，这种用于还原反应1和其他转化反应的试剂使得现在的运输更为安全
用于将聚酰胺纤维表面的酰胺基还原为仲胺。
New, Safer, NIMBA-Stabilized BH3 THF Solutions
包装
4×25, 100, 800 mL in Sure/Seal™
8, 18 L in Kilo-Lab™
View returnable container options.

Sigma Aldrich - 436879

Application
New, Safer, NIMBA-Stabilized BH3 THF Solutions

Sigma Aldrich - 15594

Other Notes
还原剂1；可将特定肟选择还原为羟胺2；作为路易斯酸介质制备手性硼烷3,4
Application
New, Safer, NIMBA-Stabilized BH3 THF Solutions

参考文献

• Hydroboration, followed by reaction of the trialkylborane with a diazoketone to give a homologated ketone: Org. Synth. Coll., 6, 919 (1988). In situ generation of "disiamyl" borane from 2-methyl-2-butene, and use of this reagent in selective hydroboration reactions: Org. Synth. Coll., 7, 258 (1990). Preparation of di-3-pinanylborane from (-)-ɑ-pinene, and its use in asymmetric hydroborations, see: Org. Synth. Coll., 7,339 (1990).
• For other reactions of borane, see Borane-dimethyl sulfide complex, L07705.
• Examples of hydroboration reactions:
• For use in the reduction of carboxylic acids to alcohols, see: Org. Synth. Coll., 7, 221 (1990).