sodium periodate

• ChemBase编号: 129547
• 分子式: INaO4
• 平均质量: 213.89184
• 单一同位素质量: 213.87390076
• SMILES: [O-][I](=O)(=O)=O.[Na+]
• Canonical SMILES: [O-][I](=O)(=O)=O.[Na+]
• InChI: InChI=1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
• InChIKey: JQWHASGSAFIOCM-UHFFFAOYSA-M

名称和登记号

名称

• IUPAC标准名: sodium periodate
• IUPAC传统名: sodium periodate
• 别名: 偏高碘酸钠, ACS; 偏高碘酸钠; 高碘酸钠; 高碘酸钠; 偏高碘酸钠; Sodium metaperiodate; Sodium periodate; Sodium periodate; Sodium metaperiodate; Sodium metaperiodate, ACS; Sodium (meta)periodate; Sodium periodate; Sodium (meta)periodate

登记号

• CAS号: 7790-28-5
• EC号: 232-197-6
• MDL号: MFCD00003534
• 默克索引号: 148640
• PubChem SID: 24899499; 24858524; 162223839; 24858306; 24862207; 24886311
• PubChem CID: 23667635
• Chemspider ID: 58683
• 维基百科标题: Sodium_periodate

理论计算性质

• Acid pKa: -42.332565
• 质子受体: 4
• 质子供体: 0
• LogD (pH = 5.5): -2.3367422
• LogD (pH = 7.4): -2.3367422
• Log P: 0.039656553
• 摩尔折射率: 19.1124 cm^3
• 极化性: 8.984818 Å^3
• 极化表面积: 74.27 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: true

分子性质

理化性质

• 溶解度: H2O: soluble0.5 M at 20 °C, clear, colorless; H2O: soluble50 mg/mL; soluble in acids; soluble in water; Soluble in water and acids
• 外观: Powder; white crystals
• 熔点: 300 °C (anhydrous) ; 175 °C (trihydrate) (decomp); 300 °C (dec.)(lit.); 300°C dec.
• 密度: 3.86; 3.865 g/cm^3 (anhydrous) ; 3/210 g/cm^3
• pH值: 3.5-5.5 (25 °C, 0.5 M in H2O)

安全信息

• 保存注意事项: Hygroscopic
• RTECS编号: SD4550000
• 欧盟危险性物质标志: 氧化性(Oxidising) (O); 刺激性(Irritant) (Xi); 有害性(Harmful) (Xn)
• 联合国危险货物编号: 1479; 3087; UN1479
• 德国WGK号: 3
• 联合国危险货物等级: 5.1
• 联合国危险货物包装类别(PG): 2; 3; II
• 危险公开号: 8-22-36/37/38; 8-36/37/38
• 安全公开号: 17-26-36/37/39; 17-26-37; 17-26-37-60; 26; R
• TSCA收录: 是
• GHS危险品标识: GHS03; GHS06; GHS07
• GHS警示词: Danger
• NFPA704:
  

  0

  2

  0
• GHS危险声明: H272-H301-H315-H319-H335; H272-H315-H319-H335
• GHS警示性声明: P220-P261-P301 + P310-P305 + P351 + P338; P221-P210-P305+P351+P338-P302+P352-P405-P501A
• 个人保护装置: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• RID/ADR: UN 1479 5.1/PG 3; UN 3087 5.1/PG 2

产品相关信息

• 纯度: ≥99.0%; ≥99.5% (RT); ≥99.8%; ≥99.8% (dried material, RT); 95+%; 98%; 99%; 99.5-100.3%; 99.8-100.3%; 99.8-100.3% dry basis; 99.8-100.3% dry basis (ACS specification)
• 浓度: 10 wt. %
• 级别: ACS reagent; ACS reagent, reag. Ph. Eur.; JIS special grade; puriss. p.a.; ReagentPlus®
• 杂质: ≤0.001% heavy metals (as Pb); ≤0.01% other halogens (as Cl); ≤0.02% other halogens (as Cl); insoluble matter, passes filter test
• 痕量阳离子: Al: ≤5 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤1 mg/kg; Mn: ≤3 ppm; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• 痕量阴离子: bromide, bromate, chloride, chlorate (as Cl-): ≤100 mg/kg; other halogens (as Cl-): ≤0.02%; sulfate (SO42-): ≤50 mg/kg
• 干燥失重: ≤0.1% loss on drying, 110 °C; ≤0.1% loss on drying, 20 °C (HV); ≤0.2% loss on drying, 110 °C
• 产品质量级别: PREMIUM
• 基质: silica gel support
• 品质说明: for the histochemical detection of polysaccharides
• 产品线: BioUltra
• abs.: absorption0.05M/350 nm, H2O cut-off
• 线性分子式: NaIO4

详细说明

Sigma Aldrich - S1147

Application
可用于在进行生物素酰肼标记前氧化糖类的试剂

Sigma Aldrich - 71859

Application
可用于在进行生物素酰肼标记前氧化糖类的试剂
Sodium periodate is use in molecular biology and carbohydrate research to cleave carbon-carbon bonds of carbohydrates alginates, chitosans, hyaluronan, scleroglucan/schizophyllan, cellulose nucleic acids other molecules rich in hydroxyls and ketones to prepare them for chemical and physical modifications.
Other Notes
Periodate oxidation of agarose gels in enzyme immobilization1; Preparation of oligonucleotide 3′-dialcohols in ribonucleoside labeling2; Cleavage of cross-linked proteins3.

Sigma Aldrich - 210048

包装
500 g in poly bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 71860

Application
可用于在进行生物素酰肼标记前氧化糖类的试剂

Sigma Aldrich - 363642

包装
25 g in glass bottle

Sigma Aldrich - 30323

Application
可用于在进行生物素酰肼标记前氧化糖类的试剂

Sigma Aldrich - 311448

Application
通过二醇的裂解和氢醌的氧化生成醌。1
包装
2.5 kg in glass bottle
5, 100, 500 g in glass bottle

Sigma Aldrich - S1878

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
可用于在进行生物素酰肼标记前氧化糖类的试剂
包装
25, 100, 500 g in glass bottle

参考文献

• For review of use in the cleavage of 1,2-diols to carbonyl compounds, see: Synthesis, 229 (1974). For application to the high-yield, racemization-free preparation of the useful intermediate isopropylidene-D-glyceraldehyde, see: Synth. Commun., 18, 337 (1988). See also: Org. Synth. Coll., 9, 450, 454 (1998).
• This reaction can be extended to the cleavage of alkenes, by use in conjunction with a reagent for the hydroxylation of alkenes, which can be regenerated by reoxidation by periodate. For use in combination with KMnO₄ (Lemieux-von Rudloff reagent), see: Can. J. Chem., 33, 1701, 1710 (1955), for cleavage of a steroidal enone, see: Org. Synth. Coll., 6, 690 (1988). The combination with OsO₄ is known as the Lemieux-Johnson reagent: J. Org. Chem., 21, 478 (1956); Synthesis, 45 (1989).
• For use in the in situ regeneration of RuO₄,see Ruthenium(III) chloride hydrate, 11043.
• Useful for selective oxidation of sulfides to sulfoxides; see, for example: Org. Synth. Coll., 9, 63 (1998).
• Alkyl halides, on heating with NaIO₄ in DMF, can be oxidized to aldehydes or ketones: Tetrahedron Lett., 44, 1375 (2003). For use, in the presence of Dibenzo-18-crown-6, A13133, in the oxidative decarboxylation of arylacetic acids to benzaldehydes and of phenacyl bromides to benzoic acids, see: Indian J. Chem. B, 35B, 151 (1996).