sodium hydride

• ChemBase编号: 129527
• 分子式: Na+
• 平均质量: 22.98977
• 单一同位素质量: 22.98976928
• SMILES: [Na+]
• Canonical SMILES: [Na+]
• InChI: InChI=1S/Na/q+1
• InChIKey: FKNQFGJONOIPTF-UHFFFAOYSA-N

名称和登记号

名称

• IUPAC标准名: sodium hydride
• IUPAC传统名: sodium hydride
• 别名: 氢化钠; Sodium hydride; Sodium hydride

登记号

• CAS号: 7646-69-7
• EC号: 231-587-3
• MDL号: MFCD00003471
• 默克索引号: 148625
• PubChem SID: 162223819
• PubChem CID: 24758
• Chemspider ID: 23144
• 维基百科标题: Sodium_hydride

理论计算性质

• 质子受体: 0
• 质子供体: 0
• 摩尔折射率: 0.0 cm^3
• 极化性: 0.394384 Å^3
• 极化表面积: 0.0 Å^2
• 可自由旋转的化学键: 0
• 里宾斯基五规则: false

分子性质

理化性质

• 溶解度: insoluble in ammonia, benzene, CCl₄, CS₂; reacts in water
• 外观: colorless to grey solid; Powder
• 熔点: 800 °C (decomposes); 800°C dec.
• 闪点: combustible
• 密度: 0.92; 1.396 g/cm^3
• 折射率: 1.470
• 标准摩尔生成焓 (ΔfH^o298): -56 kJ·mol^-1
• 标准摩尔熵 (S^o298): 40 J·mol^-1·K^-1

安全信息

• 保存注意事项: Air & Moisture Sensitive
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• 联合国危险货物编号: UN1427
• 联合国危险货物等级: 4.3
• 联合国危险货物包装类别(PG): I
• 危险公开号: 15
• 安全公开号: 7/8-24/25-43
• TSCA收录: 是
• 欧盟危险品索引: 001-003-00-X
• GHS危险品标识: GHS02; : Water-react. 1
• GHS警示词: DANGER
• NFPA704:
  

  1

  3

  0

  W
• GHS危险声明: 260; H260
• GHS警示性声明: P231+P232-P280-P233-P370+P378I-P402+P404-P501A

产品相关信息

• 纯度: 57-63% oil dispersion

参考文献

• Used in the deprotonation of DMSO to form "dimsyl sodium", a useful strong base for e.g. the Wittig reaction: J. Org. Chem., 28, 1128 (1963).
• For a review of sodium hydride-based complex reducing agents, see: Acta Chem. Scand., 44, 274 (1990).
• Widely used strong base for the irreversible formation of Na derivatives. If required, the protective oil can be removed by repeated washing and decantation with low-boiling petroleum, see, e.g.: Org. Synth. Coll., 6, 684 (1988), but for many purposes, this is not necessary, and the oil can be removed by incorporating a suitable extraction or washing step in the work-up. There are numerous Organic Syntheses references to reactions using NaH.
• CAUTION! Many literature procedures employ NaH in DMF, and this system is often used routinely by research workers as a 'convenient' general purpose strong base. It should be noted, especially when considering scale-up of such reactions, that thermal runaways have been observed with NaH/ DMF, with self-heating beginning at temperatures as low as 26^oC in some cases: Chem. Eng. News, 60(28), 5; 60(37), 5 (1982). A similar effect was also noted with N,N-dimethylacetamide. More recently also, incidents have been reported with other dipolar aprotic solvents 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone (DMPU) and Dimethyl sulfoxide (DMSO): Org. Process. Res. Dev., 7, 1030 (2003).