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Trimethaphan

产品号 DB01116 公司名称 DrugBank
CAS号 7187-66-8 公司网站 http://www.ualberta.ca/
分子式 C22H25N2OS+ 电 话 (780) 492-3111
分子量 365.5117 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 987

产品价格信息

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产品别名

标题
Trimethaphan
IUPAC标准名
3,5-dibenzyl-4-oxo-8$l^{4}-thia-3,5-diazatricyclo[6.3.0.0^{2,6}]undecan-8-ylium
IUPAC传统名
trimethaphan
商标名
Arfonad
别名
Trimetaphan
Thimethaphan
Trimetaphanum

产品登记号

PubChem SID 46508994
PubChem CID 23576
CAS号 7187-66-8

产品性质

疏水性(logP) 3.473

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description A nicotinic antagonist that has been used as a ganglionic blocker in hypertension, as an adjunct to anesthesia, and to induce hypotension during surgery. [PubChem]
Indication For the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
Pharmacology Trimethaphan is indicated for production of controlled hypotension during surgery to reduce bleeding into the surgical field and also for rapid reduction of blood pressure in the treatment of hypertensive emergencies, especially in patients with acute dissecting aneurysm, and in the emergency treatment of pulmonary edema in patients with pulmonary hypertension associated with systemic hypertension.
Affected Organisms
Humans and other mammals
External Links
Wikipedia

参考文献