Deserpidine

• 产品号: DB01089
• CAS号: 131-01-1
• 分子式: C32H38N2O8
• 分子量: 578.65272

产品别名

• 标题: Deserpidine
• IUPAC标准名: methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
• IUPAC传统名: methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
• 商标名: Canescin; Aescin; Recanescin; Raunormine; Canescine; Enduronyl; Raunorine; Raunormin; Reserpidine; beta-Escin; Harmonyl; Recanescine; Tranquinil
• 别名: Deserpidina [INN-Spanish]; Deserpidinum [INN-Latin]; Desepridine; Deresperine; Deserpine; Desmethoxyreserpine; Deserpidin

产品登记号

• PubChem CID: 8550
• PubChem SID: 46505311
• CAS号: 131-01-1

产品性质

• 疏水性(logP): 3.3

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: Deserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure and for the relief of psychotic behavior.
• Indication: For the treatment of hypertension.
• Pharmacology: Deserpidine, an alkaloid of Rauwolfia canescens, is used as an antihypertensive. Rauwolfia alkaloids work by controlling nerve impulses along certain nerve pathways. As a result, they act on the heart and blood vessels to lower blood pressure.
• Toxicity: Symptoms of overdose include dizziness or drowsiness (severe), flushing of skin, pinpoint pupils of eyes and slowed pulse.
• Affected Organisms: Humans and other mammals