Deslanoside

• 产品号: DB01078
• CAS号: 17598-65-1
• 分子式: C47H74O19
• 分子量: 943.07906

产品别名

• 标题: Deslanoside
• IUPAC标准名: 4-[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-5-{[(2R,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-5-{[(2S,4S,5S,6R)-4-hydroxy-6-methyl-5-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]-2,5-dihydrofuran-2-one
• IUPAC传统名: deslanoside
• 商标名: Cedilanid-d; Deacetyllanatoside C

产品登记号

• CAS号: 17598-65-1

产品性质

• 疏水性(logP): 0.2

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata. [PubChem]
• Indication: For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
• Pharmacology: Deslanoside is a cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.
• Toxicity: Symptoms of overdose include ventricular tachycardia, ventricular fibrillation, progressive bradyarrhythmias, or heart block.
• Affected Organisms: Humans and other mammals
• Absorption: Little absorption from the gastrointestinal tract (40%).
• Half Life: 36 hours
• Protein Binding: 20%
• External Links: Wikipedia