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Choline

产品号 DB00122 公司名称 DrugBank
CAS号 62-49-7 公司网站 http://www.ualberta.ca/
分子式 C5H14NO+ 电 话 (780) 492-3111
分子量 104.17076 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 9

产品价格信息

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产品别名

标题
Choline
IUPAC标准名
(2-hydroxyethyl)trimethylazanium
IUPAC传统名
choline
别名
(2-Hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Choline cation
Choline ion
Cholinum

产品登记号

CAS号 62-49-7
PubChem CID 305
PubChem SID 46508132

产品性质

溶解度 Soluble

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; nutraceutical
Description A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. [PubChem]
Indication For nutritional supplementation, also for treating dietary shortage or imbalance
Pharmacology This compound is needed for good nerve conduction throughout the CNS (central nervous system) as it is a precursor to acetylcholine (ACh). Choline is also needed for gallbladder regulation, liver function and lecithin (a key lipid) formation. Choline also aids in fat and cholesterol metabolism and prevents excessive fat build up in the liver. Choline has been used to mitigate the effects of Parkinsonism and tardive dyskinesia. Choline deficiencies may result in excessive build-up of fat in the liver, high blood pressure, gastric ulcers, kidney and liver dysfunction and stunted growth.
Toxicity Oral rat LD50: 3400 mg/kg
Affected Organisms
Humans and other mammals
External Links
Wikipedia
PDRhealth

参考文献