| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
A cyclohexylamido analog of penicillanic acid. [PubChem] |
| Indication |
For the treatment of bacterial infections caused by susceptible organisms. |
| Pharmacology |
Cyclacillin, a penicillin, is a cyclohexylamido analog of penicillanic acid. Cyclacillin is more resistant to beta-lactamase hydrolysis than ampicillin, is much better absorbed when given by mouth and, as a result, the levels reached in the blood and in the urine are considerably higher than those obtained with the same dose of ampicillin. Cyclacillin has been replaced by newer penicillin treatments. |
| Toxicity |
Symptoms of overdose include severe diarrhea, nausea and vomiting. |
| Affected Organisms |
| • |
Enteric bacteria and other eubacteria |
|
| Absorption |
Moderately absorbed. |
|