Oxymetazoline

• 产品号: DB00935
• CAS号: 1491-59-4
• 分子式: C16H24N2O
• 分子量: 260.37456

产品别名

• 标题: Oxymetazoline
• IUPAC标准名: 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol
• IUPAC传统名: oxymetazoline
• 商标名: Afrin Original 12 Hour Nasal Spray; Vicks Sinex 12 Hour Nasal Spray; Hazol; Drixoral Nasal Solution; Afrin Sinus 12 Hour Nasal Spray; Afrin Cherry 12 Hour Nasal Spray; Dristan Long Lasting Nasal Mist; Duramist Plus Up To 12 Hour Nasal Decongestant Spray; Iliadin; Navisin; Neo-Synephrine 12 Hour Spray; OcuClear; Sinerol; Visine L.R.; Afrin; Afrin Extra Moisturizing 12 Hour Nasal Spray; Afrin Original 12 Hour Nose Drops; Afrin Original 12 Hour Pump Mist; Dristan Long Lasting Mentholated Nasal Spray; Duration 12 Hour Nasal Spray; Genasal Nasal Spray Up to 12 Hour Relief; Nafrine; Nasal Relief 12 Hour Nasal Spray; Nasivine; Navasin; Nezeril; Nostrilla 12 Hour Nasal Decongestant; Oxylazine; Rhinofrenol; Rhinolitan; Vicks Sinex 12 Hour Ultra Fine Mist for Sinus Relief; Visine L.R
• 别名: oxymetazoline hydrochloride crystalline; Oxymetozoline; Oximetazolinum; Oxymethazoline

产品登记号

• PubChem CID: 4636
• PubChem SID: 46505622
• CAS号: 1491-59-4

产品性质

• 疏水性(logP): 3.4

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: A direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1251)
• Indication: For treatment of nasal congestion and redness associated with minor irritations of the eye
• Pharmacology: Oxymetazoline a adrenergic alpha-agonists, direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion The sympathomimetic action of oxymetazoline constricts the smaller arterioles of the nasal passages, producing a prolonged (up to 12 hours), gentle and decongesting effect. Oxymetazoline elicits relief of conjunctival hyperemia by causing vasoconstriction of superficial conjunctival blood vessels. The drug's action has been demonstrated in acute allergic conjunctivitis and in chemical (chloride) conjunctivitis.
• Affected Organisms: Humans and other mammals
• External Links: Wikipedia; Drugs.com