10-DAB

• 产品号: S2409
• CAS号: 32981-86-5
• 分子式: C29H36O10
• 分子量: 544.59014
• 保 存: -20°C

产品别名

• 标题: 10-DAB
• IUPAC标准名: (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate
• IUPAC传统名: 10-deacetylbaccatin
• 别名: 10-Deacetylbaccatin

产品登记号

• CAS号: 32981-86-5

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: cancer
Biological Activity:
10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the leaves of yew trees and 10-DAB (10-Deacetylbaccatin) is used as starting materials for numerous partial syntheses. The esterification of 10-DAB (10-Deacetylbaccatin) with longchain fatty acids can also generate an important enhancement of their kinetics and consequently their pharmacological action pattern. 10-DAB (10-Deacetylbaccatin) was first succinylated by use of dimethylaminopyridine and succinic anhydride in dried pyridine. [1][2]References on 10-DAB (10-Deacetylbaccatin)[1] Nat Prod Res. , 2006 Feb, 20(2):119-24[2] Biol Pharm Bull. , 2011, 34(4):562-6

参考文献

• Muto S et al. Biol Pharm Bull. 2011; 34(4):562-6.