您当前所在的位置:首页 > 产品中心 > 产品信息
Pioglitazone_分子结构_CAS_111025-46-8)
点击图片或这里关闭

Pioglitazone

产品号 S2590 公司名称 Selleck Chemicals
CAS号 111025-46-8 公司网站 http://www.selleckchem.com
分子式 C19H20N2O3S 电 话 (877) 796-6397
分子量 356.4387 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 1003

产品价格信息

请登录

产品别名

标题
Pioglitazone
IUPAC标准名
5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione
IUPAC传统名
pioglitazone
别名
Actos

产品登记号

CAS号 111025-46-8

产品性质

成盐信息 Free Base
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Metabolic Disease
Biological Activity:
Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator. Pioglitazone (Actos) selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) and to a lesser extent PPAR-α. Pioglitazone (Actos) modulates the transcription of the insulin-sensitive genes involved in the control of glucose and lipid metabolism in the muscle, adipose tissue, and the liver. As a result, pioglitazone (Actos) reduces insulin resistance in the liver and peripheral tissues. Pioglitazone (Actos) increases the expense of insulin-dependent glucose. Pioglitazone (Actos) decreases withdrawal of glucose from the liver. Pioglitazone (Actos) reduces quantity of glucose, insulin and glycated hemoglobin in the bloodstream. [1][2][3]References on Pioglitazone (Actos)[1] http://en.wikipedia.org/wiki/Pioglitazone, , [2] Drugs. , 2000 Aug, 60(2):333-43[3] Int J Clin Pract Suppl., 2001 Sep, (121):13-8

参考文献

  • http://www.selleckchem.com/products/pioglitazone-actos.html