Oseltamivir phosphate

• 产品号: S2597
• CAS号: 204255-11-8
• 分子式: C16H29N2O8P
• 分子量: 408.383821
• 保 存: -20°C

产品别名

• 标题: Oseltamivir phosphate
• IUPAC标准名: phosphoperoxol ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate hydrogen
• IUPAC传统名: oseltamivir phosphoperoxol hydrogen(.)
• 别名: Tamiflu

产品登记号

• CAS号: 204255-11-8

产品性质

• 成盐信息: phosphate
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Infection
Biological Activity:
Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its active metabolite, the free carboxylate of oseltamivir (GS4071). Oseltamivir phosphate (Tamiflu) serves as a competitive inhibitor towards sialic acid, found on the surface proteins of normal host cells. By blocking the activity of the viral neuraminidase enzyme, oseltamivir phosphate (Tamiflu) prevents new viral particles from being released by infected cells. Oseltamivir phosphate (Tamiflu) is an antiviral drug that slows the spread of influenza (flu) virus between cells in the body by stopping the virus from chemically cutting ties with its host cell. [1][2][3] References on Oseltamivir phosphate (Tamiflu)[1] http://en.wikipedia.org/wiki/Oseltamivir, , [2] PLoS Comput Biol., 2010 Sep 23, 6(9)[3] Microbes Infect., 2010 Sep, 12(10):778-83

参考文献

• Le L et al. PLoS Comput Biol. 2010 Sep 23; 6(9).