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Clindamycin palmitate HCl

产品号 S2596 公司名称 Selleck Chemicals
CAS号 25507-04-4 公司网站 http://www.selleckchem.com
分子式 C34H64Cl2N2O6S 电 话 (877) 796-6397
分子量 699.85276 传 真 (832) 582-8590
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保 存 -20°C Chembase数据库ID: 73258

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产品别名

标题
Clindamycin palmitate HCl
IUPAC标准名
6-{2-chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride
IUPAC传统名
6-{2-chloro-1-[(1-methyl-4-propylpyrrolidin-2-yl)formamido]propyl}-4,5-dihydroxy-2-(methylsulfanyl)oxan-3-yl hexadecanoate hydrochloride

产品登记号

CAS号 25507-04-4

产品性质

成盐信息 palmitate HCl
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Infection
Biological Activity:
Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. Clindamycin palmitate HCl is a bacterial protein synthesis inhibitor by inhibiting ribosomal translocation, in a similar way to macrolides. Clindamycin palmitate HCl does so by binding to the 50S rRNA of the large bacterial ribosome subunit. Clindamycin palmitate HCl inhibits protein synthesis in susceptible bacteria at level of 50S ribosome, thereby inhibiting peptide bond formation and causing cell death. [1][2][3]References on Clindamycin palmitate HCl[1] Antimicrob Agents Chemother., 1973 Nov, 4(5):514-20[2] http://en.wikipedia.org/wiki/Clindamycin, , [3] J Antimicrob Chemother., 1981 Jun, 7 Suppl A:37-42

参考文献

  • Louria DB et al. J Antimicrob Chemother. 1981 Jun;7 Suppl A:37-42.