Acemetacin

• 产品号: S2602
• CAS号: 53164-05-9
• 分子式: C21H18ClNO6
• 分子量: 415.82372
• 保 存: -20°C

产品别名

• 标题: Acemetacin
• IUPAC标准名: 2-({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}oxy)acetic acid
• IUPAC传统名: ({2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetyl}oxy)acetic acid
• 别名: Emflex

产品登记号

• CAS号: 53164-05-9

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Inflammation
Biological Activity:
Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.Acemetacin (Emflex) acts as a prodrug. In the body, acemetacin (Emflex) is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of acemetacin is that it reduces gastric damage when compared to indometacin. Acemetacin (Emflex) is used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. [1][2][3]References on Acemetacin (Emflex)[1] http://en.wikipedia.org/wiki/Acemetacin, , [2] Cochrane Database Syst Rev. , 2009 Jul 8, (3):CD007589[3] Ann Hepatol., 2009 Apr-Jun, 8(2):141-7

参考文献

• Chávez-Pi??a AE et al. Ann Hepatol. 2009 Apr-Jun;8(2):141-7.