Benidipine hydrochloride

• 产品号: S2017
• CAS号: 91599-74-5
• 分子式: C28H32ClN3O6
• 分子量: 542.02318
• 保 存: -20°C

产品别名

• 标题: Benidipine hydrochloride
• IUPAC标准名: 3-(3R)-1-benzylpiperidin-3-yl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
• IUPAC传统名: benidipine hydrochloride

产品登记号

• CAS号: 91599-74-5

产品性质

• 作用靶点: calcium channel
• 成盐信息: hydrochloride
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: cancer
Biological Activity:
Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. [1] Benidipine hydrochloride is used for the treatment of high blood pressure (hypertension). Benidipine hydrochloride reveals a wide range of activities in vitro and in vivo. Benidipine hydrochloride inhibits L-, N- and T-type Ca2+ channels. Benidipine hydrochloride also prevents aldosterone- induced mineralocorticoid receptor activation. Benidipine hydrochloride exhibits cardioprotective and antiartherosclerotic effects. [2]References on Benidipine HCl[1] http://en.wikipedia.org/wiki/Benidipine, , [2] Eur J Pharmacol., 2010, 635(1-3):49-55

参考文献

• Kosaka H,et al. Eur J Pharmacol. 2010;635(1-3):49-55.