Medroxyprogesterone acetate

• 产品号: S2567
• CAS号: 71-58-9
• 分子式: C24H34O4
• 分子量: 386.52436
• 保 存: -20°C

产品别名

• 标题: Medroxyprogesterone acetate
• IUPAC标准名: (1S,2R,8S,10R,11S,14R,15S)-14-acetyl-2,8,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-14-yl acetate
• IUPAC传统名: provera
• 别名: Medroxyprogesterone 17-acetate; MPA

产品登记号

• CAS号: 71-58-9

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Cancer
Biological Activity:
Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. Medroxyprogesterone acetate is used as a contraceptive, in hormone replacement therapy and for the treatment of endometriosis as well as several other indications. Medroxyprogesterone acetate is a more potent derivative of its parent alcohol medroxyprogesterone. While medroxyprogesterone is sometimes used as a synonym for medroxyprogesterone acetate ), what is normally being administered is medroxyprogesterone 17-acetate and not medroxyprogesterone. Medroxyprogesterone acetate has approximately 100 fold higher binding affinity and transactivation potency compared to medroxyprogesterone. [1][2]

参考文献

• Lenco W et al. Ann Surg. 1975 Jan;181(1):67-73.