Edaravone

• 产品号: S1326
• CAS号: 89-25-8
• 分子式: C10H10N2O
• 分子量: 174.1992
• 保 存: -20°C

产品别名

• 标题: Edaravone
• IUPAC标准名: 3-methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
• IUPAC传统名: edaravone
• 别名: Radicut; MCI-186

产品登记号

• CAS号: 89-25-8

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Cardiovascular Disease
Biological Activity:
Edaravone(MCI-186), a strong novel free radical scavenger, is used for treatment of patients with acute brain infarction. Edaravone has preventive effects on myocardial injury following ischemia and reperfusion in patients with acute myocardial infarction. Antioxidant actions of edaravone include enhancement of prostacyclin production, inhibition of lipoxygenase metabolism of arachidonic acid by trapping hydroxyl radicals, inhibition of alloxan-induced lipid peroxidation, and quenching of active oxygen, leading to protection of various cells, such as endothelial cells, against damage by reactive oxygen species (ROS). [1]

参考文献

• Watanabe T et al. Yakugaku Zasshi. 2004 Mar;124(3):99-111