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Ceftiofur hydrochloride _分子结构_CAS_103980-44-5)
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Ceftiofur hydrochloride

产品号 S2543 公司名称 Selleck Chemicals
CAS号 103980-44-5 公司网站 http://www.selleckchem.com
分子式 C19H18ClN5O7S3 电 话 (877) 796-6397
分子量 560.02352 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 73093

产品价格信息

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产品别名

标题
Ceftiofur hydrochloride
IUPAC标准名
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
IUPAC传统名
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride

产品登记号

CAS号 103980-44-5

产品性质

成盐信息 hydrochloride
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Infection
Biological Activity:
Ceftiofur hydrochloride is a hydrochloride of ceftiofur that is a broad spectrum cephalosporin. Ceftiofur hydrochloride is resistant to the antibiotic resistance enzyme beta-lactamase. Ceftiofur hydrochloride has activity against Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. Ceftiofur was more active than was ampicillin against all strains tested including beta-lactamase-producing organisms. In mice with systemic infections, ceftiofur was more active than or equivalent to ampicillin, cephalothin, cefamandole, cloxacillin, cefoperazone, or pirlimycin. These protection tests included infections with Escherichia coli, Haemophilus pleuropneumoniae, H somnus, Pasteurella haemolytica, P multocida, Salmonella typhimurium, or Staphylococcus aureus. In infant mice with E coli-induced lethal diarrhea and in mice with S aureus and E coli-induced mastitis, ceftiofur was comparable or more active than was ampicillin. [1][2][3]

参考文献

  • Yancey RJ Jr et al. Am J Vet Res. 1987 Jul; 48(7):1050-3.