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Phenytoin sodium

产品号 S2524 公司名称 Selleck Chemicals
CAS号 630-93-3 公司网站 http://www.selleckchem.com
分子式 C15H11N2NaO2 电 话 (877) 796-6397
分子量 274.24981 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 73062

产品价格信息

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产品别名

标题
Phenytoin sodium
IUPAC标准名
5,5-diphenyl-2-(sodiooxy)-4,5-dihydro-1H-imidazol-4-one
IUPAC传统名
5,5-diphenyl-2-(sodiooxy)-1H-imidazol-4-one
别名
Aleviatin; Diphenylhydantoin sodium; Eptoin;

产品登记号

CAS号 630-93-3

产品性质

成盐信息 sodium salt
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Neurological Disease
Biological Activity:
Phenytoin sodium (Dilantin) is an inactive voltage-gated sodium channel stabilizer. Phenytoin sodium is a commonly used antiepileptic. Phenytoin blocks voltage-dependent sodium channels to inhibit propagation from active electrical foci, an effect more useful for nontoxicological seizures. Phenytoin sodium (Dilantin) acts to suppress the abnormal brain activity seen in seizure by reducing electrical conductance among brain cells. Aside from seizures, Phenytoin sodium (Dilantin) is an option in the treatment of trigeminal neuralgia in the event that carbamazepine or other 1st line treatment is deemed inappropriate. [1][2]

参考文献

  • Shah AS et al. Clin Toxicol (Phila). 2010 Oct;48