Domperidone

• 产品号: S2461
• CAS号: 57808-66-9
• 分子式: C22H24ClN5O2
• 分子量: 425.91126
• 保 存: -20°C

产品别名

• 标题: Domperidone
• IUPAC标准名: 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
• IUPAC传统名: motilium
• 别名: Costi; Motillium; Motilium; Motinorm

产品登记号

• CAS号: 57808-66-9

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Metabolic Disease
Biological Activity:
Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger zone, located just outside the blood brain barrier, which - among others - regulates nausea and vomiting (area postrema on the floor of the fourth ventricle and rhomboid fossa). [1]References on Domperidone (Motilium)[1] http://en.wikipedia.org/wiki/Domperidone, ,

参考文献

• http://en.wikipedia.org/wiki/Domperidone