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Dehydroepiandrosterone

产品号 S2604 公司名称 Selleck Chemicals
CAS号 53-43-0 公司网站 http://www.selleckchem.com
分子式 C19H28O2 电 话 (877) 796-6397
分子量 288.42442 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 1482

产品价格信息

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产品别名

标题
Dehydroepiandrosterone
IUPAC标准名
(1S,2R,5S,10R,11S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-14-one
IUPAC传统名
3-β-hydroxy-5-androsten-17-one
别名
DHEA

产品登记号

CAS号 53-43-0

产品性质

作用靶点 Androgen Receptor
成盐信息 Free Base
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Cancer
Biological Activity:
Dehydroepiandrosterone(DHEA) is a 19-carbon endogenous natural steroid hormone. It is the major secretory steroidal product of the adrenal glands and is also produced by the gonads and the brain. DHEA is the most abundant circulating steroid in humans. It acts on the androgen receptor both directly and through its metabolites, which include androstenediol and androstenedione, which can undergo further conversion to produce the androgen testosterone and the estrogens estrone and estradiol. DHEA is also a potent sigma-1 agonist. It is considered a neurosteroid. [1][2]References on Dehydroepiandrosterone(DHEA)[1] http://en.wikipedia.org/wiki/Dehydroepiandrosterone, , [2] J Steroid Biochem Mol Biol., 2006 Apr, 99(1):50-8.

参考文献

  • Mo Q et al. J Steroid Biochem Mol Biol. 2006 Apr