Salidroside(Rhodioloside)

• 产品号: S2396
• CAS号: 10338-51-9
• 分子式: C14H20O7
• 分子量: 300.3044
• 保 存: -20°C

产品别名

• 标题: Salidroside(Rhodioloside)
• IUPAC标准名: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxane-3,4,5-triol
• IUPAC传统名: salidroside
• 别名: Rhodioloside

产品登记号

• CAS号: 10338-51-9

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Cancer
Biological Activity:
Salidroside (Rhodioloside; Rhodosin) is a glucoside compound with an IC50 of 4.99 ± 0.23 μg/mL for the proliferation of SACC-2. Salidroside (Rhodioloside; Rhodosin) could inhibit the proliferation of SACC-2 cells and induce SACC-2 cell apoptosis in vitro, which could be a kind of antitumor medicine in the future. Growing curve showed that SACC-2 cells of salidroside groups decreased with extending cell culture time. Immunohistochemistry staining showed that Caspase 3 and Caspase 8 were both strong positive expression in SACC-2 cells of salidroside groups, and poor positive expression in SACC-2 cells of control group, the difference was significant (P<0.01).Salidroside (Rhodioloside; Rhodosin) induces cell-cycle arrest and apoptosis in human breast cancer cells and may be a promising candidate for breast cancer treatment. [1][2][3]

参考文献

• Hu X et al. Biochem Biophys Res Commun. 2010 Jul 16;398(1):62-7.