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5-hydroxytryptophan

产品号 S2374 公司名称 Selleck Chemicals
CAS号 56-69-9 公司网站 http://www.selleckchem.com
分子式 C11H12N2O3 电 话 (877) 796-6397
分子量 220.22458 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 72998

产品价格信息

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产品别名

标题
5-hydroxytryptophan
IUPAC标准名
2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
IUPAC传统名
(+-)-5-hydroxytryptophan
别名
5-HTP

产品登记号

CAS号 56-69-9

产品性质

成盐信息 Free Base
保存条件 -20°C

产品详细信息

详细说明 (English)
Biological Activity:
5-Hydroxytryptophan(5-HTP) is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of Vitamin B6.This reaction occurs both in nervous tissue and in the liver. 5-HTP crosses the blood-brain barrier,while 5-HT does not. Excess 5-HTP, especially when administered with Vitamin B6, is thought to be metabolized and excreted. The psychoactive action of 5-HTP is derived from its effect on the production of serotonin in central nervous system tissue. More specifically, 5-HTP increases the production of serotonin. Thus, it has been used to treat diseases, e.g. depression, for which the lack of serotonin is thought to be a contributing factor. [1]

参考文献

  • http://en.wikipedia.org/wiki/5-HTP