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Dromostanolone

产品号 DB00858 公司名称 DrugBank
CAS号 58-19-5 公司网站 http://www.ualberta.ca/
分子式 C23H36O3 电 话 (780) 492-3111
分子量 360.53014 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 736

产品价格信息

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产品别名

标题
Dromostanolone
IUPAC标准名
(1S,2S,4R,7S,10R,11S,14S,15S)-2,4,15-trimethyl-5-oxotetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl propanoate
IUPAC传统名
dromostanolone
商标名
Metholone
Masteron
Permastril
Masterid
Drolban
Emdisterone
Masteril
Masterone
别名
Blackburn Compound
Drostanolone propionate
2M-DHTP
2MDTP
MDHT
Medrotestron propionate
Dromostanolone propionate
Dromostanolone proprionate
Drostanolone

产品登记号

CAS号 58-19-5

产品性质

疏水性(logP) 5.8

产品详细信息

详细说明 (English)
Item Information
Drug Groups illicit; approved
Description Drostanolone (also known as dromostanolone) is a potent synthetic androgenic anabolic steroid similar to testosterone. Drostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy.
Indication For use in females, for palliation of androgenresponsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal.
Pharmacology Dromostanolone is a synthetic androgen, or male hormone, similar to testosterone. Dromostanolone works by attaching itself to androgen receptors; this causes it to interact with the parts of the cell involved in the making of proteins. It may cause an increase in the synthesis of some proteins or a decrease in the synthesis of others. These proteins have a variety of effects, including blocking the growth of some types of breast cancer cells, stimulating cells that cause male sexual characteristics, and stimulating the production of red blood cells.
Toxicity Side effects include virilization (masculine traits in women), acne, fluid retention, and hypercalcemia.
Affected Organisms
Humans and other mammals
Absorption Well absorbed following parenteral administration.
External Links
Wikipedia

参考文献