Icariin

• 产品号: S2312
• CAS号: 489-32-7
• 分子式: C33H40O15
• 分子量: 676.6617
• 保 存: -20°C

产品别名

• 标题: Icariin
• IUPAC标准名: 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-4H-chromen-4-one
• IUPAC传统名: 5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-7-{[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}chromen-4-one

产品登记号

• CAS号: 489-32-7

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Metabolic Disease , Neurological Disease
Biological Activity:
Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively. It enhances the production of bioactive nitric oxide, as well as mimicking the effects of testosterone. It also shows antioxidant, antidepressant and nootropic effects in animal studies, as well as stimulating osteoblast activity in bone tissue which has been linked to a possible therapeutic role in the treatment of osteoporosis. [1][2]References on Icariin[1] http://en.wikipedia.org/wiki/Icariin, , [2] Urology., 2006 Dec, 68(6):1350-4.

参考文献

• Ning H et al. Urology. 2006 Dec;68(6):1350-4.