Ergosterol

• 产品号: S2297
• CAS号: 57-87-4
• 分子式: C28H44O
• 分子量: 396.64836
• 保 存: -20°C

产品别名

• 标题: Ergosterol
• IUPAC标准名: (1S,2R,5S,11R,14R,15R)-14-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-7,9-dien-5-ol
• IUPAC传统名: ergosterol

产品登记号

• CAS号: 57-87-4

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Cancer
Biological Activity:
Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2. It is turned into viosterol by ultraviolet light, and is then converted into ergocalciferol, which is a form of vitamin D. [1] Ergosterol is a component of fungal cell membranes, serving the same function that cholesterol serves in animal cells. Because ergosterol is present in fungal cell membranes yet absent in animal cell membranes, it is a useful target for antifungal drugs. It is also present in the cell membranes of some protists, such as trypanosomes. This is the basis for the use of some antifungals against West African sleeping sickness. [2][3]

参考文献

• Rajakumar K et al. Am J Public Health. 2007 Oct;97(10):1746-54.