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Artemether

产品号 S2264 公司名称 Selleck Chemicals
CAS号 71963-77-4 公司网站 http://www.selleckchem.com
分子式 C16H26O5 电 话 (877) 796-6397
分子量 298.37464 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 72920

产品价格信息

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产品别名

标题
Artemether
IUPAC标准名
(1S,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
IUPAC传统名
(1S,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane

产品登记号

CAS号 71963-77-4

产品性质

成盐信息 Free Base
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Infection
Biological Activity:
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria. Artemether has been shown to have significant anticancer and antitumor activities. It is demonstrated that artemether caused strong inhibitory effects on brain glioma growth and angiogenesis in rats. Artemether exhibits a dose- and time-dependent cytotoxicity, and induced apoptosis and G2 cell cycle arrest in ovarian cancer cell lines, human leukemia HL60 cells, and human pancreatic cancer BxPC-3 and AsPC-1 cells. [1][2]

参考文献

  • Jiao Y et al. Acta Pharmacol Sin. 2007 Jul;28(7):1045-56.